A health worker talks to people as they wait to register next to the Transvaco coronavirus disease (COVID-19) vaccine train, after South Africa’s rail company Transnet turned the train into a COVID-19 vaccination center on rails to help the government speed up its vaccine rollout in the country’s remote communities, at the Springs train station on the East Rand, South Africa, August 30, 2021. Picture taken August 30, 2021. REUTERS/Siphiwe Sibeko

JOHANNESBURG, Nov 25 (Reuters) – South African scientists have detected a new COVID-19 variant in small numbers and are working to understand its potential implications, they said on Thursday.

The variant – called B.1.1.529 – has a “very unusual constellation” of mutations, which are concerning because they could help it evade the body’s immune response and make it more transmissible, scientists told reporters at a news conference.

Early signs from diagnostic laboratories suggest the variant has rapidly increased in the most populated province of Gauteng and may already be present in the country’s other eight provinces, they said.

South Africa has confirmed around 100 specimens as B.1.1.529, but the variant has also been found in Botswana and Hong Kong, with the Hong Kong case a traveller from South Africa. As many as 90% of new cases in Gauteng could be B.1.1.529, scientists believe.

“Although the data are limited, our experts are working overtime with all the established surveillance systems to understand the new variant and what the potential implications could be,” South Africa’s National Institute for Communicable Diseases said in a statement.

Read more: South Africa detects new coronavirus variant, still studying its mutations

South Africa has requested an urgent sitting of a World Health Organization (WHO) working group on virus evolution on Friday to discuss the new variant.

Health Minister Joe Phaahla said it was too early to say whether the government would impose tougher restrictions in response to the variant.

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South Africa was the first country to detect the Beta variant last year.

Beta is one of only four labelled “of concern” by the WHO because there is evidence that it is more contagious and vaccines work less well against it.

The country detected another variant, C.1.2, earlier this year, but it has not displaced the more common Delta variant and still only accounts for a small percentage of genomes sequenced in recent months.

(Reporting by Alexander Winning Editing by Angus MacSwan and Mark Potter)